Lactoferrin as an immunity ‘super-ingredient’
Lactoferrin is one of the latest ingredients in the spotlight of consumer health and wellbeing, joining a long line up of proteins, vitamins and minerals that occur naturally in dairy products. It is increasingly being viewed as an immunity ‘super-ingredient’, reported to be active against some viruses, bacteria and fungi³ ⁴.
Lactoferrin is a naturally occurring, iron-binding glycoprotein that is produced by the human body. Those derived from bovine milk have a very similar structure to the equivalent human protein.
It acts as one of the body’s whistle-blowers. When a pathogen enters the body, lactoferrin can activate the immune system via cytokine-like signals, prompting the release of antibodies. It has also been found to play an important role in modulating inflammation⁵, which can sometimes occur during an immune response. Lactoferrin achieves this by competing with a molecule called IL-8 that is involved in immune cell activation³.
As well as joining the body’s wall of defence, lactoferrin plays an active role in the attack of pathogens. It inhibits the binding of viruses to certain receptors of human host cells (such as the ACE-II receptor) and deprives them of nutrients needed for growth, like iron³.